US MLS Soccer 2025  Betting & Odds 2025

Bet on US MLS markets such as: Arsenal v Southampton; Liverpool v Nottm Forest; Crystal Palace v Everton; Man City v Arsenal; Fulham v Leeds and set your preferred back (bet for) and lay (bet against) odds with Betfair Exchange. Take the US MLS odds offered by other players or if you think an outcome won’t happen, set the US MLS odds for other players to bet on!

US MLS

Betting on US MLS is simple. Browse over 167 markets, including English Premier League - Winner 2022/23. Place a lay bet if you think Man City will lose, or a back bet if you think Man City will win.

US MLS markets: betting statistics

The English Premier League event with the most matched amount is Arsenal v Southampton.